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Breo Ellipta (fluticasone furoate and vilanterol)

Indications

• Use Breo Ellipta to treat asthma in patients aged 18 years and older. It helps improve breathing and reduce asthma attacks when taken regularly.
• You can use it to manage chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It helps decrease the frequency of flare-ups and improves overall lung function.

Dosage and Administration

• Inhale Breo Ellipta exactly as prescribed by your doctor, typically once daily.
• Use the inhaler at the same time each day to maintain consistent medication levels in your system.
• Follow the instructions provided with your inhaler to ensure proper use and effective delivery of the medication.
• Rinse your mouth with water and spit it out after inhaling the medication to help prevent mouth and throat infections.
• Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
• Do not use Breo Ellipta more than once daily.
• Avoid exhaling into the inhaler to prevent moisture from affecting the powder.
• Do not use Breo Ellipta to relieve sudden breathing problems; it is not a rescue inhaler.
• Avoid stopping the medication suddenly without consulting your doctor, as this may worsen your condition.

Mechanism of Action

Breo Ellipta combines two medications: fluticasone furoate, a corticosteroid that reduces inflammation in the airways, and vilanterol, a long-acting beta-agonist (LABA) that relaxes the muscles around the airways to improve breathing. Together, they help control and prevent asthma symptoms and COPD exacerbations.

Contraindications

• Do not use Breo Ellipta if you are allergic to fluticasone, vilanterol, or any other ingredients in the inhaler.
• Avoid using it if you have a severe milk protein allergy, as the inhaler contains lactose.
• Do not use Breo Ellipta for sudden breathing problems; use a fast-acting rescue inhaler instead.

Side Effects

Common Side Effects

• Headache
• Throat irritation
• Hoarseness
• Cough
• Back pain

Serious Side Effects

• Severe allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)
• High blood pressure
• Chest pain
• Fast or irregular heartbeat
• Signs of infection (fever, chills, persistent sore throat)
• Eye problems (blurred vision, eye pain)

Precautions

• Inform your doctor if you have a history of heart disease, high blood pressure, diabetes, thyroid problems, or liver disease before using Breo Ellipta.
• You should monitor for signs of oral thrush (white patches in your mouth) and seek medical advice if symptoms occur.
• Avoid exposure to chickenpox or measles while using Breo Ellipta, as it can weaken your immune system.
• Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting Breo Ellipta.
• Regularly monitor your lung function and overall health while using this medication.

Storage Instructions

• Store Breo Ellipta at room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep the inhaler away from direct heat, light, and moisture.
• Do not store it in the bathroom.
• Keep out of reach of children and pets.
• Discard the inhaler 6 weeks after opening the foil tray or when the counter reads “0,” whichever comes first.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/204275s012lbl.pdf