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Imodium (loperamide)

Indication

Imodium (loperamide) is used for the rapid relief of diarrhea symptoms. Imodium (loperamide) makes the stools more solid and less.

Dosage and Administration

• Do follow the prescribed dosage based on age, weight, and severity of symptoms.
• Take orally, usually after each loose stool or as directed by a healthcare provider.
• Take chewable tablets on an empty stomach and chew thoroughly before swallowing.
• Let rapidly dissolving tablets dissolve on the tongue without water.
• Ensure adequate fluid intake to prevent dehydration.
• Seek medical advice if no improvement after 2 days or if new symptoms develop.
• Do not exceed 8 milligrams in 24 hours if self-treating or 16 milligrams in 24 hours under the healthcare provider’s direction. 

Imodium  Ingredient

Medicinal ingredient: Loperamide hydrochloride

Non medicinal ingredient: D&C Yellow #10, FD&C Blue #1, FD&C Yellow #6, magnesium stearate, lactose monohydrate, pregelatinized starch and sodium starch glycolate.

Mechanism of Action

Imodium works by slowing down the movement of the gut. This helps to decrease the number of bowel movements and makes the stool less watery.

Contraindications

• Pediatric patients less than 2 years of age. 

• Known hypersensitivity to loperamide hydrochloride or any excipients. 

• Abdominal pain without diarrhea. 

• Acute dysentery, acute ulcerative colitis. 

• Bacterial enterocolitis caused by invasive organisms. 

• Pseudomembranous colitis. 

Side Effects of Imodium

Common Side Effects:

• Dizziness 

• Drowsiness 

• Stomach cramps 

Serious Side Effects:

• Watery or bloody diarrhea 

• Stomach pain or bloating 

• Ongoing or worsening diarrhea 

• Fast or irregular heartbeat, shortness of breath, dizziness 

• Severe constipation, nausea, vomiting 

• Heart rhythm changes, chest pain, trouble breathing 

• Allergic reactions such as skin rash, itching, swelling 

Precautions

• Monitor for allergic reactions, including anaphylaxis. 

• Use with caution in hepatic impairment; monitor closely for signs of CNS toxicity. 

• Do not make dosage adjustments in renal impairment. 

• Use with caution in elderly patients; avoid in those taking drugs prolonging QT interval or with risk factors for Torsades de Pointes. 

Storage Instructions of Imodium

• Store at 15-25°C (59-77°F) 

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017694s052lbl.pdf