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Serevent Diskus (salmeterol) 

Indications 

• Asthma: Serevent Diskus is used for the long-term treatment of asthma and to prevent asthma attacks. It is not for acute bronchospasm relief. 
• Chronic Obstructive Pulmonary Disease (COPD): It helps manage COPD symptoms, including chronic bronchitis and emphysema, by improving breathing and reducing the number of flare-ups. 

Dosage and Administration 

• Use Serevent Diskus exactly as prescribed by your doctor. 
• Inhale the medication twice daily (morning and evening), approximately 12 hours apart. 
• Follow the instructions on how to correctly use the Diskus inhaler to ensure proper dosage. 
• Rinse your mouth with water after each use to reduce the risk of oral infections. 
• Inform your doctor of all medications, supplements, and herbal products you are currently taking. 
• Continue using Serevent Diskus regularly, even if you feel well, to maintain control of your asthma or COPD. 
• Do not use Serevent Diskus to treat an acute asthma attack or sudden breathing problems; use a fast-acting inhaler instead. 
• Avoid skipping doses; use Serevent Diskus consistently as prescribed to maintain its effectiveness. 
• Do not exceed the prescribed dose to prevent potential side effects or overdose. 
• Avoid using another long-acting beta-agonist (LABA) while using Serevent Diskus unless directed by your doctor. 
• Do not stop using Serevent Diskus without consulting your doctor, even if you experience side effects. 

Mechanism of Action 

Serevent Diskus works by stimulating beta-2 receptors in the smooth muscle of the airways, leading to bronchodilation. This action relaxes the muscles around the airways, making it easier to breathe and preventing symptoms such as wheezing, coughing, and shortness of breath in asthma and COPD patients. 

Contraindications 

• Do not use if you are allergic to salmeterol or any ingredients in Serevent Diskus. 
• Avoid use in the treatment of acute asthma attacks or severe episodes of COPD. 
• Not recommended for individuals with a history of severe hypersensitivity to milk proteins. 
• Consult your doctor if you have heart disease, high blood pressure, diabetes, thyroid disorders, or seizures before using this medication. 
• Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. 

Side Effects 

Common Side Effects 

• Headache 
• Dizziness 
• Throat irritation 
• Dry mouth 
• Hoarseness 
• Muscle pain 
• Cough 

Serious Side Effects 

• Severe allergic reactions (rash, itching, swelling of the face/tongue/throat) 
• Chest pain or tightness 
• Fast or irregular heartbeat 
• Severe dizziness or fainting 
• Worsening breathing problems 
• Signs of infection (fever, chills, persistent sore throat) 
• High blood sugar (increased thirst, frequent urination, confusion) 

Precautions 

• Inform your doctor of any existing health conditions, especially heart disease, high blood pressure, diabetes, thyroid disorders, or seizures. 
• Regularly monitor for any side effects and report any severe or unusual symptoms to your healthcare provider. 
• Avoid activities that increase the risk of injury or breathing difficulties. 
• Use Serevent Diskus consistently to maintain its effectiveness in managing asthma or COPD symptoms. 
• Discuss all medications, supplements, and herbal products you are taking with your healthcare provider to avoid interactions. 
• Inform your healthcare provider if you need to stop Serevent Diskus temporarily for any reason. 

Storage Instructions 

• Store Serevent Diskus at room temperature between 68°F and 77°F (20°C and 25°C). 
• Keep the Diskus in a dry place, away from moisture and direct sunlight. 
• Do not store it in the bathroom to avoid exposure to humidity. 
• Keep out of reach of children and pets. 

References 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020692s047lbl.pdf