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Formulation : Tablet
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Amaryl (glimepiride)

Indications

  • Used to improve blood sugar control in adults with type 2 diabetes as part of a treatment plan that may include diet and exercise.
  • Can be used alone or in combination with other diabetes medications such as metformin or insulin to enhance blood sugar control.

Dosage and Administration

  • Take the tablet exactly as prescribed by your doctor, usually once daily with breakfast or the first main meal.
  • Swallow the tablet whole with water.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider.
  • Follow a balanced diet and exercise regimen as recommended by your healthcare provider.
  • Do not skip meals after taking Amaryl, as it can cause low blood sugar (hypoglycemia).
  • Avoid alcohol as it can increase the risk of hypoglycemia.
  • Do not take more than the prescribed dose; adhere strictly to your doctor’s instructions.

Mechanism of Action

Glimepiride, the active ingredient in Amaryl, is a sulfonylurea. It works by stimulating the pancreas to release insulin, which helps lower blood sugar levels. Additionally, it helps the body use insulin more efficiently, improving overall blood glucose control in patients with type 2 diabetes.

Contraindications

  • Allergic Reaction: Do not use if you are allergic to glimepiride, other sulfonylureas, or any ingredients in Amaryl.
  • Type 1 Diabetes: Not suitable for individuals with type 1 diabetes.
  • Diabetic Ketoacidosis: Do not use if you have diabetic ketoacidosis (a serious diabetes complication).

Side Effects

Common Side Effects:

  • Low blood sugar (hypoglycemia)
  • Dizziness
  • Headache
  • Nausea
  • Weight gain

Serious Side Effects:

  • Severe allergic reactions (rash, itching/swelling, severe dizziness, trouble breathing)
  • Liver problems (yellowing of the skin or eyes, dark urine, severe stomach pain)
  • Blood disorders (unusual bleeding or bruising, signs of infection such as fever and sore throat)
  • Severe hypoglycemia (confusion, seizures, loss of consciousness)

Precautions

  • Regular Monitoring: Regularly check your blood sugar levels as advised by your doctor.
  • Kidney and Liver Function: Inform your doctor if you have kidney or liver problems, as dose adjustments may be necessary.
  • Surgery: Inform your healthcare provider if you are scheduled for surgery, as your medication regimen may need to be adjusted.
  • Other Medications: Inform your doctor about all other medications you are taking to avoid potential interactions, especially other diabetes medications and NSAIDs.
  • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Storage Instructions

  • Store at room temperature between 20°C to 25°C (68°F to 77°F).
  • Keep away from excessive moisture; do not store in the bathroom.
  • Protect from light to maintain efficacy.
  • Keep out of reach of children to prevent accidental ingestion.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020496s027lbl.pdf

Additional information

Brand Name:

Amaryl

Scientific Name:

Glimepiride

Other Names:

Amaryl, Glimepiride, Glimy

Strength(s):

1mg, 2mg, 3mg, 4mg

Quantities Available:

30, 90, 100, 180

Formulation:

Tablet

The information above is provided by third parties to Prescriptionpoint.com for Amaryl (Glimepiride). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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