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Fosamax (alendronate)

Indications

Fosamax tablets are prescribed for the following conditions:

  • Osteoporosis in Postmenopausal Women: Used to treat osteoporosis in postmenopausal women to increase bone mass and reduce the risk of fractures, including hip and spine fractures.
  • Osteoporosis in Men: Used to treat osteoporosis in men to increase bone mass and reduce the risk of fractures.
  • Glucocorticoid-Induced Osteoporosis: Used to prevent and treat osteoporosis induced by glucocorticoid medications in men and women.

Dosage and Administration

  • Take Fosamax exactly as prescribed by your doctor. The recommended dosage and duration of treatment depend on the specific condition being treated.
  • Take Fosamax first thing in the morning, at least 30 minutes before eating, drinking (except water), or taking other medications.
  • Ensure adequate calcium and vitamin D intake while taking Fosamax, as directed by your healthcare provider.
  • Do not lie down for at least 30 minutes after taking Fosamax to avoid reflux and irritation of the esophagus.
  • Do not take Fosamax with mineral water, coffee, tea, juice, or any other beverages other than plain water.
  • Do not chew or crush.

Mechanism of Action

Fosamax is a medication that helps prevent bone loss. It works by stopping cells that break down bone. By doing this, it helps bones stay stronger and reduces the chance of fractures in people with osteoporosis.

Contraindications

Fosamax should not be used if you:

  • Are Unable to Stand or Sit Upright: Due to the risk of esophageal irritation and ulceration, Fosamax is contraindicated in patients who cannot stand or sit upright for at least 30 minutes.
  • Have Hypersensitivity to Alendronate: Any known hypersensitivity to Alendronate or any component of the formulation.

Side Effects

Common Side Effects:

  • Gastrointestinal upset (nausea, abdominal pain, indigestion)
  • Esophageal irritation or ulceration
  • Bone, joint, or muscle pain
  • Headache
  • Dizziness or vertigo

Serious Side Effects:

  • Osteonecrosis of the jaw (rare but serious)
  • Atypical fractures of the femur (rare but serious)
  • Allergic reactions (rash, itching, swelling)
  • Visual disturbances
  • Fatigue or weakness

Precautions

  • Monitor for Adverse Effects: Be vigilant for any signs of gastrointestinal upset, esophageal irritation, or allergic reactions while taking Fosamax.
  • Regular Dental Check-ups: Inform your dentist that you are taking Fosamax and schedule regular dental check-ups to monitor for signs of osteonecrosis of the jaw.
  • Bone Health Monitoring: Regularly monitor bone mineral density and assess fracture risk as recommended by your healthcare provider.
  • Inform About Medical History: Inform your doctor about any medical conditions you have, especially gastrointestinal disorders or kidney problems.
  • Pregnancy and Breastfeeding: Fosamax is not recommended during pregnancy or breastfeeding due to potential harm to the fetus or infant.

Storage Instructions

  • Keep Fosamax tablets at room temperature, between 68°F to 77°F (20°C to 25°C).
  • Store the tablets in the original container, tightly closed, and protect from moisture.
  • Ensure that the medication is stored safely out of the reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021575s017lbl.pdf

Additional information

Brand Name:

Fosamax

Scientific Name:

Alendronate

Other Names:

Alendronate, Alendronic Acid, Fosamax, Osteofos

Strength(s):

10mg, 35mg, 70mg

Quantities Available:

4, 12, 100

Formulation:

Tablet

The information above is provided by third parties to Prescriptionpoint.com for Fosamax (Alendronate). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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