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Clomid (clomiphene) 

Indications  

Clomid is indicated for the treatment of ovulatory dysfunction in women who wish to become pregnant, including: 

  • Women with polycystic ovary syndrome (PCOS) 
  • Women with irregular ovulation 
  • Women with unexplained infertility 

Dosage and Administration  

  • Take Clomid exactly as prescribed by your healthcare provider. Typically, the first dose is taken on the fifth day of the menstrual cycle, continuing for five days. 
  • Undergo regular monitoring of ovulation and hormone levels as advised by your healthcare provider. 
  • Have regular sexual intercourse during the ovulation period for the best chance of conception. 
  • Drink plenty of water while taking Clomid to stay hydrated. 
  • Do not skip doses or change your dosage without consulting your healthcare provider. 
  • Do not use Clomid for more than six cycles unless advised by your healthcare provider. 
  • Do not take other medications without consulting your healthcare provider, especially hormonal treatments. 

Mechanism of Action 

Clomid helps your body release the hormones needed for ovulation. It works by attaching estrogen sensors to the brain, making your body think there isn’t enough estrogen. This makes the pituitary gland produce more follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which encourage the growth and release of a mature egg. 

Contraindications 

Clomid is contraindicated in patients with: 

  • Known hypersensitivity or allergy to Clomiphene Citrate or any of its ingredients. 
  • Pregnancy (Pregnancy Category X). 
  • Liver disease or history of liver dysfunction. 
  • Abnormal uterine bleeding of undetermined origin. 
  • Ovarian cysts or enlargement not due to polycystic ovarian syndrome. 
  • Uncontrolled thyroid or adrenal dysfunction. 
  • Organic intracranial lesions such as pituitary tumors. 

Side Effects  

Common Side Effects 

  • Hot flashes 
  • Bloating 
  • Nausea 
  • Breast tenderness 
  • Headache 
  • Mood swings 

Serious Side Effects: 

  • Visual disturbances (e.g., blurred vision, seeing spots) 
  • Ovarian hyperstimulation syndrome (OHSS) 
  • Severe abdominal pain 
  • Rapid weight gain 
  • Shortness of breath 
  • Severe allergic reactions (e.g., hives, difficulty breathing) 

Precautions 

  • Watch for signs of ovarian enlargement or cyst formation. 
  • Discontinue use if you experience visual symptoms. 
  • Be aware of the increased risk of multiple pregnancies, such as twins or triplets. 

Storage Instructions 

  • Store Clomid capsules at controlled room temperature, between 59-86°F (15-30°C). 
  • Protect from heat, light, and excessive humidity. 
  • Keep the medication in closed containers. 

References 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/016131s026lbl.pdf  

Additional information

Brand Name:

Clomid

Scientific Name:

Clomiphene

Other Names:

Clomid, Siphene, Siphene-M

Strength(s):

25mg, 50mg, 100mg

Quantities Available:

10, 20, 30, 50, 90, 100

Formulation:

Scored Tablet, Tablet

The information above is provided by third parties to Prescriptionpoint.com for Clomid (Clomiphene). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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