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What is Cambia?
Cambia is a brand-name medication that can only be obtained with a doctor’s prescription. This medication contains the active ingredient diclofenac potassium, a non-steroidal anti-inflammatory drug or NSAID. It has analgesic, anti-inflammatory, and antipyretic effects. Therefore, diclofenac can be used to relieve pain from different kinds of conditions.
Cambia’s mechanism of action is not completely understood. Still, it may be related to the inhibition of cyclooxygenase (COX-1 and COX-2), blocking the synthesis of pro-inflammatory and pain-related prostaglandin mediators, resulting in decreased prostaglandins in peripheral tissues.
What is Cambia used for
Cambia (diclofenac potassium) powder for oral solution is used for the acute treatment of migraine with or without aura in people who are 18 years of age and older.
This medication is not used to prevent migraine attacks and treat cluster headaches.
Cambia dosage and direction
Cambia comes as a powder for oral solution, and an individual dose sachet has 50 mg of diclofenac potassium.
For acute treatment of migraine, administer 1 packet (50 mg) of Cambia orally once daily. Empty the contents of one Cambia packet into a cup containing 30-60 ml (1-2 ounces or 204 tbsps) of water. Mix it well and consume it immediately. Do not use any other kinds of liquid, only water.
Taking Cambia with food may reduce its effectiveness or delay pain relief action compared to taking it without meals. However, food may lower possible stomach and intestinal side effects. Do not eat a high-fat meal because Cambia may not work.
Take this drug exactly as prescribed to you by your doctor. Read the medication guide and instruction sheets carefully and follow the prescription label instructions.
To decrease the risk of stomach bleeding and other side effects, take the lowest dose of this medication. Do not take longer than the recommended dose and duration.
Do not take Cambia (diclofenac) if you are allergic to its active and inactive ingredients or if you have a history of an asthma attack or serious allergic reactions after using aspirin or an NSAID
Cambia (diclofenac) can raise your risk of stroke or fatal heart attack, even without any risk factors. You should not use Cambia before and after heart bypass surgery, specifically coronary artery bypass graft (CABG).
This medication can also cause stomach or intestinal bleeding, ulcers, and tears of the esophagus, stomach, and intestines without warning symptoms anytime during use that may cause death.
Before taking this medication, inform your doctor if you have heart disease, increased blood pressure, stomach ulcers or bleeding, asthma, kidney or liver problems, a headache that is different from your usual migraine, irregular heartbeats, shortness of breath, chest pain, or are a smoker.
Before taking this medication, it is important to tell your doctor if you are pregnant, and think you might be or plan to be pregnant. Taking an NSAID such as Cambia can cause kidney or serious heart problems in your unborn baby and possible complications during pregnancy and delivery.
Avoid taking a new medicine without consulting your doctor first.
Cambia drug interactions
Inform your healthcare provider about all the medications you take, including non-prescription and prescription medications, herbal products, vitamins, and supplements. Some medications can interact with Cambia and may cause serious side effects.
If you’re taking any of the following drugs, let your doctor know:
-Aspirin, ibuprofen, and other NSAIDS. Using diclofenac with these medications may increase adverse effects.
-Anticoagulants or blood thinners such as warfarin. Using Cambia with these medications results in a risk of serious GI bleeding.
-ACE inhibitors/blockers such as captopril, enalapril, benazepril, fosinopril, lisinopril, quinapril, moexipril, trandolapril, and ramipril. NSAIDs such as Cambia can decrease the antihypertensive effect of these drugs.
-Diuretics such as triamterene, torsemide, furosemide, hydrochlorothiazide, acetazolamide. Cambia may antagonize or raise the risk of renal failure when used with these drugs.
-Lithium, using this drug together with Cambia, patients should be observed for signs of lithium toxicity.
-Methotrexate, its toxicity may be enhanced by NSAIDS.
-Cyclosporine, concomitant use with Cambia, may raise its nephrotoxicity.
-Inhibitors of Cytochrome P450 2C9, may affect diclofenac’s pharmacokinetics.
Cambia side effects
Many medications, including Cambia, can cause some mild or serious side effects. Not everyone who takes this medication can experience the side effects listed below.
Here are the common side effects of Cambia:
-Nausea and vomiting
-Headache, dizziness, drowsiness
-Pain in the arms and legs
If the symptoms listed above persist and become bothersome or worse, contact your doctor and ask for medical advice.
Seek emergency medical help if you experience a serious allergic reaction shown by rash, itching, swelling of the face, lips, tongue, or throat, severe dizziness, and trouble breathing. Also, if you have signs of a heart attack or stroke shown by sudden numbness or weakness on one side of the body, chest pain radiating to the jaw or shoulder, sweating, sudden headache, dizziness, slurred speech, vision changes, and feeling short of breath.
Discontinue using Cambia and contact your healthcare provider immediately if you experience the following:
-Symptoms similar to flu.
-Skin rash or blisters with high body temperature (fever).
-Heart problems are shown by feeling short of breath, swelling, and rapid weight gain.
-Kidney problems are shown by painful or difficult urination, changes in the amount of urine (little to no urine), feeling tired or short of breath, and swelling of the arms or legs.
-Liver problems are shown by diarrhea, nausea, pain at the upper right side of the stomach, tiredness, itching, dark-colored urine, and yellowing of the skin or eyes (jaundice).
-Signs of stomach bleeding such as coughing up blood or vomit that appears like coffee grounds, or bloody or tarry stools.
Frequently asked questions about Cambia
How long does Cambia work?
Cambia works within 15 minutes in some patients. Cambia (diclofenac potassium) is rapidly absorbed and achieves plasma concentrations in 15 minutes.
Can I drink alcohol while on Cambia?
It is not recommended to drink alcohol while taking Cambia because alcohol can increase your risk of stomach bleeding.
Does Cambia make you drowsy?
Some people may experience nausea, vomiting, constipation, diarrhea, dizziness, or drowsiness when taking this product. Be sure to tell your doctor or pharmacist about any of these effects if they last or get worse.
Who should not take Cambia?
Women should not use CAMBIA during pregnancy, especially after 29 weeks, unless directed to do so by their healthcare provider as it may cause problems for the unborn child or complications during delivery.
Breastfeeding women and those planning to breastfeed also should not take this drug as it is unknown whether it passes into breast milk.
9sachets, 18sachets, 27sachets
Powder for Oral Solution
The information above is provided by third parties to Prescriptionpoint.com for Cambia (Diclofenac Potassium). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.