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Amerge (naratriptan)

Indications

• Used to treat acute migraine headaches with or without aura in adults.
• It helps to relieve headache pain, nausea, and sensitivity to light and sound.
• Aids in restoring normal activities by reducing migraine symptoms.

Dosage and Administration

• Take Amerge exactly as prescribed by your healthcare provider.
• Take one tablet at the first sign of a migraine for the best results. If the headache comes back after relief, you may take a second dose at least 4 hours after the first dose.
• Swallow the tablet whole with water.
• Do not take more than 2 doses in 24 hours.
• Avoid taking Amerge for more than four headaches in one month without consulting your doctor.
• Do not use Amerge to prevent migraines; it is intended only for treating active migraine episodes.
• Do not take Amerge if you have certain types of heart conditions or a history of stroke.

Mechanism of Action

Amerge belongs to a class of drugs called triptans. It works by narrowing blood vessels around the brain and reducing substances in the body that can trigger headache pain, nausea, and other migraine symptoms. This helps to alleviate the symptoms of a migraine and restore your ability to function.

Contraindications

• Do not use it if you are allergic to Naratriptan or any other ingredients in Amerge.
• Avoid use if you have certain heart conditions such as coronary artery disease.
• Not recommended if you have had a stroke or transient ischemic attack (TIA).
• Do not use it if you have uncontrolled high blood pressure.
• Avoid taking Amerge if you have severe liver or kidney disease.

Side Effects

Common Side Effects

• Dizziness
• Drowsiness
• Nausea
• Tingling or numbness in fingers or toes
• Dry mouth

Serious Side Effects

• Chest pain or tightness
• Shortness of breath
• Irregular heartbeat
• Severe stomach pain
• Vision changes

Precautions

• Inform your doctor of your full medical history, especially if you have risk factors for heart disease.
• Tell your doctor about all other medications you are taking to avoid potential interactions.
• Do not take Amerge if you are pregnant or breastfeeding without consulting your doctor.
• Be cautious if you have conditions such as diabetes or high cholesterol, as these can increase the risk of heart problems.
• Avoid driving or operating heavy machinery if you feel drowsy or dizzy after taking Amerge.

Storage Instructions

• Store at room temperature between 68°F and 77°F (20°C and 25°C).
• Keep away from moisture and heat.
• Store in a safe place out of the reach of children.
• Keep the tablets in their original packaging until use.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020763s011lbl.pdf