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Zyprexa (olanzapine)

Indications

Zyprexa is prescribed for the following conditions:

• Schizophrenia
• Bipolar Disorder
• Depression

Dosage and Administration

• Take exactly as prescribed by your healthcare provider.
• Taken with or without meals.
• Have regular follow-up appointments to monitor your response.
• Use a pill organizer to maintain consistency and not miss any doses.
• Always consult your doctor before making changes.
• Do not increase or decrease your dose without consulting your doctor.
• Do not consume alcohol as it can increase the risk of side effects.
• Do not miss doses as it can reduce the effectiveness of the treatment.
• Do not stop Zyprexa suddenly as it can cause withdrawal symptoms.

Mechanism of Action

Olanzapine works by affecting the actions of certain natural chemicals (neurotransmitters) in the brain. It primarily targets serotonin and dopamine receptors, which play a crucial role in mood regulation, perception, and behavior. By balancing these neurotransmitters, Zyprexa helps to alleviate symptoms of mental health disorders such as schizophrenia and bipolar disorder.

Contraindications

• Allergic Reaction: Do not take Zyprexa if you have a known allergy to olanzapine or any other ingredients in the tablet.
• Severe Liver Problems: Not recommended for individuals with significant liver impairment.
• Uncontrolled Heart Problems: Avoid if you have severe heart conditions, especially irregular heart rhythms.
• Glaucoma: Not suitable for patients with narrow-angle glaucoma.

Side Effects

Common Side Effects:

• Headache
• Weight Gain
• Drowsiness
• Dry Mouth
• Increased Appetite
• Constipation

Serious Side Effects:

• Severe Allergic Reactions (rash, itching, swelling)
• Uncontrolled Movements (tardive dyskinesia)
• High Blood Sugar (hyperglycemia)
• Seizures
• Severe Dizziness or Fainting
• Unusual Thoughts or Behavior

Precautions

• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Diabetes Monitoring: Regularly check blood sugar levels if you have diabetes, as Zyprexa can raise blood sugar.
• Weight Management: Monitor your weight regularly, as this medication can cause significant weight gain.
• Avoid Overheating: Stay hydrated and avoid overheating, especially during exercise or hot weather.
• Alertness: This medication can cause drowsiness. Avoid driving or operating heavy machinery until you know how Zyprexa affects you.
• Regular Health Checks: Have regular blood tests to monitor liver function, blood sugar, and lipid levels.

Storage Instructions

• Store at room temperature between 68°F to 77°F (20°C to 25°C).
• Store in a dry place away from moisture and direct light.
• Keep the medication out of reach of children and pets.
• Keep Zyprexa in its original container until it’s time to take it.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020592s062021086s040021253s048lbl.pdf