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Drug Name Dosage Quantity Price Buy Now
Xigduo XR 5/1000mg 56 $125.00 Add To Cart
Xigduo XR 10/500mg 28 $96.00 Add To Cart
Xigduo XR 10/500mg 84 $275.00 Add To Cart
Xigduo XR 10/1000mg 84 $380.00 Add To Cart
Xigduo XR
Dosage: 5/1000mg
Quantity: 56
Price: $125.00
Xigduo XR
Dosage: 10/500mg
Quantity: 28
Price: $96.00
Xigduo XR
Dosage: 10/500mg
Quantity: 84
Price: $275.00
Xigduo XR
Dosage: 10/1000mg
Quantity: 84
Price: $380.00

What is Xigduo XR used for?

Xigduo XR uses are the following: 

  • To control blood sugar level along with proper exercise and diet in adults with type 2 diabetes mellitus. 
  • To lower the risk of hospitalization due to heart failure in people with type 2 diabetes mellitus and heart disease.

This drug contains two medications, dapagliflozin, and metformin. It belongs to a class of drugs known as antidiabetics, biguanides; antidiabetics, SGLT2 Inhibitors.  

Xigduo XR dosage  

  • Xigduo XR 5/1000 mg 

5 mg dapagliflozin and 1000 mg metformin hydrochloride is one of the available dosage forms of Xigduo XR. For better blood glucose control of patients who are not using dapagliflozin yet, the recommended initial dose for dapagliflozin is 5mg once daily. If you want to lower the risk of hospitalization for heart failure, dapagliflozin 10 mg once daily is the recommended dose. 

  • Xigduo XR 10 mg 1000 mg 

The recommended maximum daily dose for dapagliflozin is 10 mg and for metformin is 2000 mg. 

For those who are taking an evening dose of metformin, XR should skip their last dose before initiating Xigduo XR. 

The initial dose of this medication should be individualized and based on the patient’s current treatment regimen. This drug should be taken once daily in the morning with meals. Swallow this medication whole. Never crush, chew, or cut. 

You may check the pricing of Xigduo XR by clicking here. 

Xigduo XR side effects 

The following are the most common side effects of Xigduo XR: 

  • Headache 
  • Diarrhea
  • Stuffy or runny nose
  • Sore throat
  • Urinary tract infection
  • Yeast infections (vagina and penis) 

If these symptoms persist, worsen, or become worrisome, tell your doctor at once. 

Lactic acidosis is the accumulation of lactic acid in the body. Tell your doctor right away if any of the following symptoms occur: 

  • Stomach symptoms occur after the first days of taking this drug. 
  • Drop-in blood pressure 
  • Low body temperature
  • Slow heart rhythms and irregular heart rate
  • Dizziness
  • Feeling tired or very weak
  • Trouble breathing
  • Unusual muscle pain 

Ketoacidosis is an increased ketone in the blood or urine. Stop taking this drug and call your doctor immediately if the following symptoms occur:  

  • Nausea 
  • Vomiting  
  • Tiredness
  • Stomach pain
  • Trouble breathing.

Dehydration is the loss of body water and salt. This may also happen when taking Xigduo XR. It leads to the following symptoms: 

  • Lightheadedness
  • Dizziness
  • Fainting
  • Weakness especially when you suddenly stand up (orthostatic hypotension) Discuss with your doctor how to avoid dehydration.

Kidney problems (swelling of the legs/feet, changes in the amount of urine, fluid loss due to vomiting, diarrhea or being exposed to the sun for a long time) and serious urinary tract infections (burning sensation or pain while urinating, urinary frequency and urgency, blood in the urine, pelvic pain) are serious side effects of Xigduo XR. Inform your doctor immediately if any symptoms of these two conditions occur.

This drug can also cause a rare but serious bacterial infection in the anus or around it and genitals (perineum) called Fournier’s gangrene. Get medical help right away if you experience the following: fever, tiredness or uncomfortable feeling, and pain, swelling, and redness around the anus or genitals.

Watch out for signs and symptoms of allergic reactions such as trouble breathing, rash, itching, and swelling of the face, lips, tongue, or throat. Seek medical attention at once if this happens. 


Xigduo XR depression

Depression is one of the possible side effects of Xigduo XR but the incidence of experiencing it has not been reported or known. 

Additional information

Brand Name:

Xigduo XR

Scientific Name:

Dapagliflozin/Metformin Hcl

Other Names:

Xigduo XR


5/1000mg, 10/500mg, 10/1000mg

Quantities Available:

28, 56, 84


ER Tablet

The information above is provided by third parties to for Xigduo XR (Dapagliflozin/Metformin Hcl). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.