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Seroquel XR (quetiapine extended release)

Indications 
seroquel-xr

  • Schizophrenia: Seroquel XR is used for the treatment of schizophrenia in adults.
  • Bipolar Disorder: It is prescribed for the treatment of manic and depressive episodes associated with bipolar disorder.
  • Major Depressive Disorder (MDD): Seroquel XR is used as an adjunctive treatment to antidepressants in adults with major depressive disorder.

Dosage and Administration

  • Take Seroquel XR exactly as prescribed by your doctor.
  • Swallow the tablets whole with a full glass of water.
  • Take the medication once daily, preferably in the evening.
  • Follow your doctor’s instructions on the dosage and schedule, and do not adjust the dose without consultation.
  • Inform your doctor of all medications, supplements, and herbal products you are currently taking.
  • Continue taking Seroquel XR even if you feel well, as it helps to maintain mental balance. :
  • Do not crush, chew, or break the tablets, as this can affect the drug’s extended-release mechanism.
  • Avoid skipping doses; take Seroquel XR consistently as prescribed to maintain its effectiveness.
  • Do not take more than the prescribed dose to prevent potential side effects or overdose.
  • Avoid consuming alcohol while taking Seroquel XR, as it can increase the risk of side effects.
  • Do not stop taking Seroquel XR without consulting your doctor, even if you experience side effects.

Mechanism of Action

Seroquel XR works by altering the actions of chemicals in the brain, primarily by blocking dopamine and serotonin receptors. This helps to restore the balance of these neurotransmitters, improving symptoms of schizophrenia, bipolar disorder, and major depressive disorder.

Contraindications

  • Do not use if you are allergic to quetiapine or any ingredients in Seroquel XR.
  • Avoid use in the treatment of dementia-related psychosis in elderly patients due to increased risk of death.
  • Not recommended for individuals with a history of severe liver disease.
  • Consult your doctor if you have a history of cardiovascular disease, seizures, or diabetes before taking this medication.
  • Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Side Effects

Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Weight gain
  • Increased appetite
  • Constipation
  • Upset stomach

Serious Side Effects

  • Severe allergic reactions (rash, itching, swelling of the face/tongue/throat)
  • Uncontrollable movements or muscle stiffness
  • Signs of high blood sugar (increased thirst, frequent urination, confusion)
  • Severe dizziness or fainting
  • Changes in vision or eye pain
  • Severe headache, confusion, or seizures
  • Signs of infection (fever, chills, persistent sore throat)

Precautions

  • Inform your doctor of any existing health conditions, especially cardiovascular disease, seizures, liver disease, or diabetes.
  • Regularly monitor for any side effects and report any severe or unusual symptoms to your healthcare provider.
  • Avoid activities that require alertness, such as driving, until you know how Seroquel XR affects you.
  • Take Seroquel XR consistently to maintain its effectiveness in managing symptoms of schizophrenia, bipolar disorder, or major depressive disorder.
  • Discuss all medications, supplements, and herbal products you are taking with your healthcare provider to avoid interactions.
  • Inform your healthcare provider if you need to stop Seroquel XR temporarily for any reason.

Storage Instructions

  • Store Seroquel XR tablets at room temperature between 68°F and 77°F (20°C and 25°C).
  • Keep the medication in its original container, tightly closed, and away from moisture and light.
  • Do not store it in the bathroom to avoid exposure to humidity.
  • Keep out of reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022047Orig1s042lbl.pdf

Additional information

Brand Name:

Seroquel XR

Scientific Name:

Quetiapine, Quetiapine Fumarate SR

Other Names:

Quetiapine XL, Quetiapine XR, Qutan SR, Qutipin SR, Seroquel XL, Seroquel XR

Strength(s):

50mg, 100mg, 150mg, 200mg, 300mg, 400mg

Quantities Available:

50, 60, 100, 120

Formulation:

Extended Release Tablet

The information above is provided by third parties to Prescriptionpoint.com for Seroquel XR (Quetiapine Fumarate SR). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.


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