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PEG 3350 (polyethylene glycol 3350)

Indications

The medication is used to relieve occasional constipation by drawing water into the bowel, softening stools, and increasing the frequency of bowel movements.

Dosage and Administration

• Follow the dosing instructions provided by your doctor or on the package.
• Measure the recommended dose using the provided measuring cap or a measuring spoon.
• Dissolve the powder in a glass of water, juice, soda, coffee, or tea (4 to 8 ounces).
• Stir until the powder is completely dissolved and drink the solution right away.
• Take the solution at the same time each day for best results.
• Stay hydrated by drinking plenty of fluids throughout the day.
• Do not take more than the recommended dose.
• Do not take the solution if you are allergic to polyethylene glycol.
• Do not use the solution for longer than one week unless directed by your doctor.
• Do not skip doses or stop taking the medication without consulting your doctor.
• Do not mix the powder with alcoholic beverages.

Mechanism of Action

PEG 3350 (Polyethylene glycol 3350) works as an osmotic laxative. It draws water into the bowel, which helps to soften the stool and increase bowel movements, making it easier to pass.

Contraindications

• Allergic Reaction: Do not use it if you are allergic to Polyethylene glycol or any of the ingredients in the powder.
• Bowel Obstruction: Avoid using the medication if you have a known or suspected bowel obstruction, as it may worsen the condition.
• Kidney Disease: Do not use it if you have severe kidney disease without consulting your doctor.

Side Effects

Common Side Effects:

• Bloating
• Nausea
• Gas
• Diarrhea
• Stomach cramps

Serious Side Effects:

• Severe or prolonged diarrhea
• Blood in stools
• Severe stomach pain
• Allergic reactions (rash, itching, swelling, dizziness)

Precautions

• Monitor for Side Effects: Report any severe or persistent side effects to your doctor.
• Inform about Medical History: Let your doctor know if you have a history of bowel obstruction, kidney disease, or any other medical conditions.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Hydration: Ensure you drink plenty of fluids to stay hydrated while taking this medication.
• Avoid Overuse: Do not use for more than one week without medical advice, as long-term use can lead to dependency.

Storage Instructions

• Keep the powder at a temperature between 68°F and 77°F (20°C to 25°C).
• Store in a dry place, away from moisture and humidity.
• Ensure the medication is stored securely away from children and pets.
• Dispose of unused or expired powder properly, following local regulations or pharmacy guidelines.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019011s025lbl.pdf