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Norpace (disopyramide)

Indications

• Norpace is indicated for the treatment of certain types of serious irregular heartbeats (arrhythmias) such as ventricular tachycardia.
• Used to restore normal heart rhythm and maintain a regular, steady heartbeat.

Dosage and Administration

• Take Norpace exactly as prescribed by your doctor, typically every 6 to 12 hours.
• Swallow the capsule whole with a full glass of water.
• Take Norpace consistently at the same times each day to maintain even levels of the medication in your bloodstream.
• Consult your doctor if you miss a dose; take it as soon as you remember unless it is almost time for the next dose.
• Have regular medical check-ups to monitor heart function and adjust the dosage if necessary.
• Do not chew, crush, or break the capsule; swallow it whole.
• Avoid consuming alcohol while taking Norpace, as it can increase the risk of side effects.
• Do not skip doses or stop taking the medication without consulting your doctor, as this can worsen your condition.
• Avoid taking Norpace with grapefruit or grapefruit juice, as it can interfere with the medication’s effectiveness.

Mechanism of Action

Norpace contains disopyramide, an antiarrhythmic medication. It works by blocking certain electrical signals in the heart that can cause an irregular heartbeat. This helps to stabilize the heart rhythm and prevent episodes of arrhythmias.

Contraindications

• Do not use Norpace if you have a known allergy to disopyramide or any other ingredients in the capsule.
• Avoid using Norpace if you have severe heart failure, certain types of heart block without a pacemaker, or cardiogenic shock.
• Not recommended for use in individuals with myasthenia gravis.

Side Effects

Common Side Effects

• Dry mouth
• Blurred vision
• Constipation
• Difficulty urinating
• Dizziness

Serious Side Effects

• Severe allergic reactions (rash, itching, swelling, difficulty breathing)
• Worsening of irregular heartbeats or new arrhythmias
• Signs of heart failure (shortness of breath, swelling of the ankles/feet, unusual tiredness)
• Signs of low blood sugar (tremors, sweating, confusion)
• Severe gastrointestinal symptoms (persistent nausea/vomiting, stomach pain)

Precautions

• Inform your doctor about any existing medical conditions, especially heart problems, kidney or liver disease, glaucoma, or prostate issues, before using Norpace.
• Be cautious if you have a history of urinary retention or an enlarged prostate, as Norpace can worsen these conditions.
• Regularly monitor blood sugar levels if you have diabetes, as Norpace can affect glucose control.
• Discuss the risks and benefits of Norpace if you are pregnant, planning to become pregnant, or breastfeeding.
• Avoid driving or operating heavy machinery if you experience dizziness or blurred vision.
• Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions.

Storage Instructions

• Store Norpace capsules at room temperature (15°C to 30°C) in a dry place, away from moisture and heat.
• Keep the bottle tightly closed when not in use.
• Do not use Norpace if the capsules show signs of discoloration, damage, or deterioration.
• Dispose of any unused or expired medication properly, following local regulations or guidelines.
• Keep Norpace out of reach of children and pets.

References

https://www.drugs.com/pro/norpace.html