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Formulation : Tablet
Drug Name Dosage Quantity Price Buy Now
Movantik 12.5mg 30 $245.00 Add To Cart
Movantik 25mg 30 $255.00 Add To Cart
Dosage: 12.5mg
Quantity: 30
Price: $245.00
Dosage: 25mg
Quantity: 30
Price: $255.00

Movantik (naloxegol)


Movantik is prescribed for adults experiencing constipation caused by opioid medications used to manage chronic, non-cancer pain. It helps alleviate the bowel movement issues that often accompany long-term opioid use.

Dosage and Administration

  • Administer Movantik at least 1 hour before the first meal of the day or 2 hours after the meal for optimal absorption.
  • Swallow the tablets whole.
  • Adhere to the dosage and administration guidelines provided by your healthcare provider.
  • Drink plenty of water throughout the day to support bowel movements.
  • Do not crush, chew, or split the tablets to ensure the medication is delivered effectively.
  • Avoid adjusting your dosage without consulting your healthcare provider, as this can affect the effectiveness and safety of the treatment.
  • Avoid grapefruit and grapefruit juice as these can interfere with the absorption of Movantik, potentially increasing side effects.
  • Take Movantik consistently as prescribed to maintain its effectiveness.

Mechanism of Action

Movantik (Naloxegol) is a peripherally acting mu-opioid receptor antagonist (PAMORA). It works by selectively blocking the opioid receptors in the gastrointestinal tract without affecting the pain-relief functions of opioids in the central nervous system. This action helps restore normal bowel function without diminishing pain relief.


  • Known Hypersensitivity to Naloxegol: Do not take Movantik if you have a known allergy to Naloxegol or any of its components.
  • Bowel Obstruction: Avoid using Movantik if you have a history of bowel obstruction or are at high risk of developing this condition.
  • Severe Liver Impairment: Patients with severe liver problems should not take Movantik as it may exacerbate their condition.

Side Effects

Common Side Effects:

  • Headache
  • Nausea
  • Diarrhea
  • Abdominal pain
  • Gas

Serious Side Effects:

  • Severe abdominal pain
  • Persistent diarrhea
  • Symptoms of a serious allergic reaction (rash, itching/swelling, severe dizziness, trouble breathing)


  • Consult Your Doctor if Pregnant or Breastfeeding: Discuss with your healthcare provider before starting Movantik if you are pregnant or planning to breastfeed.
  • Inform About All Medications: Share a complete list of your current medications with your doctor to avoid harmful interactions.
  • Monitor for Severe Abdominal Pain: Contact your healthcare provider if you experience severe, persistent abdominal pain, as this could indicate a serious condition.
  • Adjust for Kidney Problems: Your doctor may need to adjust your dose if you have kidney issues.
  • Avoid Driving if Drowsy: Movantik can cause dizziness; ensure you know how it affects you before driving or operating machinery.

Storage Instructions

  • Keep Movantik tablets at 68°F to 77°F (20°C to 25°C).
  • Store the medication in its original container to protect it from moisture and light.
  • Ensure that Movantik is stored in a safe place away from children to prevent accidental ingestion.


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12.5mg, 25mg

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The information above is provided by third parties to for Movantik (Naloxegol). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.