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Lopressor (metoprolol tartrate)

Indications

• Lopressor is used to treat high blood pressure, helping to prevent strokes, heart attacks, and kidney problems.
• It is prescribed for the management of angina (chest pain) to improve exercise tolerance and reduce the frequency of angina attacks.
• Lopressor is used in the treatment of heart attacks to reduce the risk of death and improve survival rates.
• It helps manage certain types of abnormal heart rhythms by stabilizing the heart rate.

Dosage and Administration

• Take Lopressor exactly as prescribed by your healthcare provider.
• Take the medication with or immediately after a meal to enhance absorption.
• Take at the same time each day to maintain consistent blood levels.
• Take the tablet whole with a full glass of water; do not crush or chew.
• Do not miss doses as it can lead to a sudden increase in blood pressure or chest pain.
• Do not consume alcohol as it can increase the risk of side effects like dizziness or fainting.
• Do not stop taking Lopressor suddenly without consulting your doctor, as it can worsen your condition.

Mechanism of Action

Lopressor (metoprolol tartrate) is a beta-blocker that works by blocking the action of certain natural chemicals in the body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart, improving blood flow and reducing the risk of heart-related complications.

Contraindications

• Severe Bradycardia: Do not use the medication if you have a very slow heart rate.
• Cardiogenic Shock: Avoid if you are in shock caused by heart failure.
• Severe Heart Block: Contraindicated in patients with severe conduction disorders like second or third-degree heart block without a pacemaker.
• Severe Heart Failure: Not recommended for use in patients with decompensated heart failure requiring intensive treatment.
• Allergy to Metoprolol: Do not use if you have a known allergy to metoprolol or any other beta-blocker.

Side Effects

Common Side Effects:

• Dizziness
• Fatigue
• Depression
• Shortness of breath
• Bradycardia (slow heart rate)
• Cold extremities

Serious Side Effects:

• Severe dizziness or fainting
• Shortness of breath, even with mild exertion
• Swelling of the ankles or feet
• Rapid weight gain
• Severe bradycardia (very slow heart rate)
• Signs of an allergic reaction (hives, difficulty breathing, swelling of face, lips, tongue, or throat)

Precautions

• Monitor Blood Pressure and Heart Rate: Regular monitoring of blood pressure and heart rate is essential to ensure the medication is working effectively and safely.
• Diabetes: Inform your doctor if you have diabetes, as Lopressor can mask the symptoms of low blood sugar.
• Asthma or COPD: Use with caution in patients with respiratory conditions like asthma or chronic obstructive pulmonary disease (COPD).
• Thyroid Disorder: Lopressor can mask symptoms of hyperthyroidism (overactive thyroid).
• Surgery: Inform your surgeon or anesthesiologist that you are taking Lopressor before any surgical procedure.

Storage Instructions

• Store Lopressor at room temperature between 20°C to 25°C (68°F to 77°F).
• Store in a dry place, away from moisture and light.
• Keep the tablets in their original container until ready to use.
• Ensure the medication is stored safely away from children.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/017963s074lbl.pdf