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Inderal (propranolol)

Indications

Inderal is indicated for-

• Hypertension (High Blood Pressure)
• Used to lower high blood pressure, reducing the risk of heart attacks, strokes, and kidney problems.
• Angina Pectoris (Chest Pain)
• Helps prevent chest pain caused by reduced blood flow to the heart.
• Arrhythmias (Irregular Heartbeat)
• Treats irregular heart rhythms by slowing down the heart rate and regulating its rhythm.
• Migraine Prevention
• Reduces the frequency and severity of migraine headaches.
• Tremors
• Controls essential tremors (uncontrollable shaking) and tremors associated with certain medical conditions.

Dosage and Administration

• Take Inderal exactly as prescribed by your healthcare provider.
• Take the tablet at the same time each day to maintain a steady level in your bloodstream.
• Take it with or without food, according to your preference or as advised by your doctor.
• Attend follow-up appointments to monitor your blood pressure and heart rate.
• Do not double dose. If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip the missed dose and continue with your regular schedule.
• Do not stop taking Inderal suddenly without consulting your doctor, as it can lead to rebound effects and worsen your condition.
• Do not crush or chew the tablets.

Mechanism of Action

Inderal belongs to a class of medications called beta-blockers. It works by blocking the effects of adrenaline on the beta receptors in the heart and blood vessels. This leads to a decrease in heart rate, cardiac output, and blood pressure, thereby reducing the workload on the heart and improving blood flow to the heart muscle.

Contraindications

• Allergic Reactions: Do not use it if you are allergic to Propranolol or any of the ingredients in Inderal.
• Heart Conditions: Avoid use if you have certain heart conditions, such as heart block, bradycardia (slow heart rate), or heart failure, without consulting your doctor.
• Asthma or COPD: Contraindicated in patients with asthma or chronic obstructive pulmonary disease (COPD), as it can worsen breathing difficulties.
• Low Blood Pressure: Not recommended for patients with hypotension (low blood pressure).
• Diabetes: Use with caution in diabetic patients, as it can mask symptoms of low blood sugar.

Side Effects

Common Side Effects:

• Fatigue
• Dizziness
• Nausea
• Cold hands or feet
• Sleep disturbances

Serious Side Effects:

• Slow heart rate
• Wheezing or difficulty breathing
• Depression or mood changes
• Fainting
• Swelling of the hands, ankles, or feet

Precautions

• Regular Monitoring: Regularly monitor your blood pressure and heart rate as advised by your doctor.
• Inform About Other Medications: Inform your healthcare provider about all other medications you are taking, including over-the-counter drugs and supplements, to avoid interactions.
• Asthma or COPD: Use with caution in patients with asthma or COPD, as it can exacerbate breathing difficulties.
• Diabetes Monitoring: Diabetic patients should closely monitor their blood sugar levels while taking Inderal.
• Avoid Activities Requiring Alertness: Be cautious when driving or operating machinery until you know how Inderal affects you, as it can cause dizziness or fatigue.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Inderal in these conditions is not fully established.

Storage Instructions

• Store at room temperature between 20°C to 25°C (68°F to 77°F).
• Keep in a dry place away from moisture and direct sunlight.
• Store the tablets in their original packaging until it’s time to take them.
• Do not use the tablets beyond their expiration date. Dispose of any expired medication properly.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/016418s080,016762s017,017683s008lbl.pdf