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Haldol (haloperidol)

Indications

Haldol is indicated for-

• Schizophrenia: Used to manage symptoms such as hallucinations, delusions, and thought disturbances.
• Tourette’s Syndrome: Effective in controlling tics and vocal utterances in people with severe Tourette’s disorder.
• Behavioral Disorders: Helps control severe behavioral problems in children and adults, especially in those with hyperactivity, aggression, or difficulty paying attention.

Dosage and Administration

• Take Haldol tablets with or without food; however, taking them with food may help reduce stomach upset.
• Swallow the tablets whole with a glass of water; do not crush or chew them.
• Adhere strictly to the prescribed dosage and schedule set by your doctor.
• Try to take the medicine at the same time each day to maintain a consistent level in your bloodstream.
• Avoid missing doses; if you miss a dose, take it as soon as you remember unless it is almost time for the next dose.
• Do not take two doses at the same time to make up for a missed dose.
• Do not consume alcohol while taking Haldol, as it can increase certain side effects.
• Do not stop taking Haldol suddenly without consulting your doctor, as this can cause withdrawal symptoms.

Mechanism of Action

Haldol works by blocking the action of dopamine, a neurotransmitter in the brain that affects mood and behavior. By reducing the effects of dopamine, Haldol helps to manage symptoms of psychosis and other mental health disorders.

Contraindications

• Severe Heart Problems: Not for use in individuals with known severe heart issues such as prolonged QT interval, severe heart failure, or recent heart attack.
• Central Nervous System Depression: Avoid in patients experiencing severe CNS depression, including coma.
• Parkinson’s Disease: Not recommended for individuals with Parkinson’s disease.
• Allergy to Haloperidol: Do not use it if you have a known allergy to haloperidol or any ingredients in the tablets.

Side Effects

Common Side Effects:

• Drowsiness
• Dizziness
• Dry mouth
• Blurred vision
• Constipation
• Weight gain

Serious Side Effects:

• Severe allergic reactions (rash, itching, swelling)
• Irregular heartbeats or palpitations
• Severe muscle stiffness or tremors
• Symptoms of neuroleptic malignant syndrome (fever, muscle rigidity, altered mental status)
• Uncontrollable movements of the face and tongue (tardive dyskinesia)
• Severe dizziness or fainting

Precautions

• Medical History: Inform your doctor about your full medical history, especially any heart problems, liver issues, or history of seizures.
• Pregnancy and Breastfeeding: Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Blood Monitoring: Regular blood tests may be needed to monitor for any adverse effects, especially if you are on long-term therapy.
• Mental Alertness: Be aware that Haldol can affect your mental alertness; avoid driving or operating heavy machinery until you know how it affects you.
• Avoid Overheating: Be cautious in hot weather or during exercise to avoid overheating and dehydration.

Storage Instructions

• Store Haldol tablets at room temperature, between 59°F to 86°F (15°C to 30°C).
• Protect from moisture, avoid storing it in the bathroom.
• Ensure the medication is kept out of reach of children and pets.
• Store in the original container with the lid tightly closed.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/015923s092lbl.pdf