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What is Ddavp (Desmopressin) Nasal Spray?
Ddavp medication is a brand-name prescription medication administered into the nose (intranasal use). It has an active substance called desmopressin acetate, a man-made analogue of the natural hormone arginine vasopressin. Desmopressin Ddavp Nasal Spray belongs to two classes of drugs: antidiuretics and antihemorrhagics. It works by replacing vasopressin to help balance the amount of salt and water in the body. It acts on bleeding episodes by increasing Factor VIII, ristocetin cofactor, and von Willebrand factor, resulting in less bleeding for those with low amounts of these agents. This drug is mainly eliminated in the urine. Ddavp Nasal Spray is contraindicated in patients with or history of hyponatremia and with moderate to severe renal impairment.
What is Ddavp (Desmopressin) Nasal Spray Used For?
Ddavp uses as follows:
- Ddavp is used to treat central diabetes insipidus, a condition that causes thirst and frequent urination.
- This medication is also used to control temporary excessive thirst and the production of an abnormally large amount of urine that can happen after a head injury or certain types of brain surgery.
- This medication is also used to treat or prevent bleeding episodes in Hemophilia A patients and von Willebrand’s disease.
- Another use of this medication is to treat adults with nocturia (a condition in which one wakes up at night to urinate).
The safety and efficacy of Ddavp medication use in children younger than 3 months are unknown.
What Are Ddavp (Desmopressin) Nasal Spray Side Effects?
Like most medications, Ddavp (Desmopressin) Nasal Spray has unwanted side effects that can be mild or severe, temporary or permanent. Not everyone who uses this medication will experience the following common DDAVP side effects.
If you have any of the following and they become persistent and bothersome, contact your doctor or pharmacist.
- Stomach pain
- Congestion or stuffy/runny nose, sneezing, nostril pain/discomfort
- Sore throat
- Increased blood pressure
- Flushing of the face or redness of the skin
- Increased sensitivity (of the eyes) to light, eye itching
- Back pain
The following Ddavp medication side effects don’t occur very often but can become serious if you do not get immediate medical help.
Inform your healthcare provider at once if you experience any of the following as well.
- Loss of appetite (anorexia)
- Low blood pressure
- Swelling of the face or hands
- Low sodium in the blood manifested by weakness, tiredness, confusion, stiffness, ache, uncoordinated muscles
- Too much fluid in the body is shown by nausea, vomiting, weight gain
Discontinue using this medication and seek medical attention right away if you experience any of the following serious side effects of DDAVP (Desmopressin) nasal spray:
- Severe allergic reaction manifested by rash, hives, itching, swelling of the face, lips, tongue, or throat, trouble breathing or swallowing, and severe dizziness.
- Headache, confusion, hallucinations, drowsiness
- Chest pain, fast or pounding heartbeat
- Muscle pain or weakness
- Restlessness, irritability
- Rapid weight gain
- Seizure, coma, or death
Ddavp (Desmopressin) Nasal Spray Dosage Information
The usual Ddavp dose in adults with diabetes insipidus is 10 mcg to 40 mcg (0.1 to 0.4mL) daily. It can be given all at once (single dose) or divided into 2-3 doses.
For children 3 months to 12 years old, the recommended DDAVP dose nasal spray form is 5 mcg to 30 mcg (0.05 to 0.3 mL) daily, either as a single dose or divided into 2 doses. Fluid restriction must be observed.
Ddavp (Desmopressin) Nasal Spray comes in a 5-ml bottle with a spray pump delivering 50 sprays of 10 mcg. Its compression pump delivers 0.1mL (10mcg) of Ddavp (desmopressin acetate) per spray.
This product can only deliver doses of 0.1 mL (10mcg) or multiples of 0.1 mL. This should be primed before the first use. To prime, press down four times. Then the bottle will now deliver 10 mcg of medicine per spray.
Warning and Interactions Ddavp (Desmopressin) Nasal Spray
DDAVP indications include treatment of central diabetes insipidus, temporarily increased thirst and urination that can happen after a head injury or certain types of brain surgery, for the prevention of bleeding in people with mild hemophilia A and mild von Willebrand’s disease and treatment adults with nocturia. Your doctor may have suggested this medication for other indications besides those mentioned earlier. Discuss it with your doctor if you are unsure why you are given this medication for other uses.
Before you use this medication, tell your doctor if you are allergic to any of its active and inactive ingredients or if you have any allergies.
Before starting to use this medication, tell your doctor about your medical history and any conditions you have, such as conditions that may increase your risk of fluid/mineral imbalance like Cystic Fibrosis, kidney disease, heart problems (heart failure, blocked blood vessels), high blood pressure, hyponatremia (low level of sodium in the blood), bleeding/clotting problems, and urge to drink excessive water without being thirsty.
If you have scarring in the nose, nasal congestion, swelling, or blockage, or recently had nasal surgery, you should not use this nasal spray. These conditions can affect the amount of this medication that is absorbed by the body, which might not be effective for you.
Dehydration needs to be corrected first before starting treatment with this medicine.
This medication should only be used during pregnancy if it is required or the benefits outweigh the risks. It is unknown whether this medicine passes into breast milk. Consult your doctor before you start breastfeeding.
FAQ’s Ddavp Nasal Spray
How does Ddavp work?
Ddavp is a man-made form of vasopressin hormone. This medication works in the kidneys to reduce the amount of urine, which will balance fluids in the body.
What does Ddavp stand for?
DDAVP stands for 1-deamino-8-D-arginine vasopressin.
How much does Ddavp cost?
Ddavp Nasal Spray prices will depend on your dose. Prescription Point offers both brand and generic versions of this medication. Check the top of this page for your options.
How long does Ddavp last?
The effect of this medication may last 8 to 12 hours or longer. Doses of 0.1 mg to 0.2 mg produced antidiuretic effects lasting up to 8 hours. For the 0.4 mg dose, antidiuretic effects were observed for up to 12 hours.
Where to Buy Ddavp Nasal Spray?
When you buy Ddavp Nasal Spray online, the costs vary based on site, dosage, and quantity. For DDAVP, buy online from our drugstore and see how much you’ll save.
How Much Does Ddavp (Desmopressin) Nasal Spray Cost?
Ddavp costs vary depending on the strength and frequency you are supposed to take. You may check for the Ddavp cost at the top of this page.
Desmopressin Acetate, Minirin
The information above is provided by third parties to Prescriptionpoint.com for DDAVP (Desmopressin). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.