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Cortef (hydrocortisone)

Indications

• Cortef tablets are prescribed for:
• Treating adrenal gland disorders such as Addison’s disease
• Reducing inflammation caused by various conditions such as arthritis, allergic reactions, and asthma
• Managing certain skin conditions like eczema and psoriasis
• Providing hormone replacement therapy in certain conditions where the body does not produce enough cortisol naturally

Dosage and Administration

• Take Cortef exactly as prescribed by your doctor.
• Swallow the tablets whole with a full glass of water.
• Take the medication with food or milk to help prevent stomach upset.
• Follow your doctor’s instructions carefully for the timing and frequency of doses.
• Do not suddenly stop taking Cortef without consulting your doctor, as it may lead to withdrawal symptoms.
• Do not crush or chew the tablets unless advised by your doctor.

Mechanism of Action

Cortef belongs to a class of medications called corticosteroids. It works by reducing inflammation and suppressing the immune system’s response to certain diseases or conditions.

Contraindications

• Cortef tablets should not be used if you have:
• Allergy to hydrocortisone or any other corticosteroids
• Serious infections, unless under specific medical supervision
• Active untreated tuberculosis
• Recent vaccination with live vaccines

Side Effects

Common side effects:

• Upset stomach
• Headache
• Dizziness
• Increased appetite
• Difficulty sleeping
• Weight gain

Serious side effects:

• Severe allergic reactions (rash, itching, swelling)
• Changes in mood or behavior (depression, mood swings)
• Increased blood sugar levels
• Vision changes
• Muscle weakness
• Irregular heartbeat

Precautions

• Inform your doctor about any other medications or supplements you are taking before starting Cortef.
• Monitor your blood sugar levels regularly while taking Cortef, especially if you have diabetes.
• Avoid contact with people who have contagious diseases such as chickenpox or measles while taking Cortef, as it may increase the risk of infection.
• Discuss with your doctor the risks and benefits of using Cortef during pregnancy or breastfeeding.

Storage Instructions

• Store Cortef tablets at room temperature away from moisture and heat.
• Keep the medication out of reach of children.
• Do not store Cortef in the bathroom.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/008697s032_33lbl.pdf