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Calan SR (verapamil)

Indications

• Calan SR capsules are indicated for the management of hypertension (high blood pressure) to lower blood pressure and reduce the risk of cardiovascular events such as heart attacks and strokes.
• It is also used for the treatment of angina (chest pain) and certain types of arrhythmias (irregular heartbeats).

Dosage and Administration

• Take Calan SR exactly as prescribed by your doctor, usually once daily.
• Swallow the capsule whole with a full glass of water.
• Take Calan SR at the same time each day to maintain an even level of medication in your blood.
• Follow any dietary and exercise recommendations provided by your healthcare provider to support your treatment.
• Do not crush, chew, or break the capsule.
• Do not exceed the prescribed dose of Calan SR or take it more frequently than directed by your doctor.
• Avoid suddenly stopping Calan SR without consulting your doctor, as it may worsen your condition.
• Avoid consuming grapefruit or grapefruit juice while taking Calan SR, as it can interfere with the medication’s effectiveness.

Mechanism of Action

• Calan SR contains Verapamil, a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels. This relaxation helps to lower blood pressure, improve blood flow, and reduce the workload on the heart.

Contraindications

• Do not use Calan SR if you have a known allergy to Verapamil or any other ingredients in the capsules.
• Avoid Calan SR if you have severe left ventricular dysfunction, severe hypotension (low blood pressure), or certain types of heart block (unless you have a pacemaker).
• Consult your doctor before using Calan SR if you have severe liver disease or a history of heart failure.

Side Effects

Common Side Effects:

• Dizziness or lightheadedness
• Headache
• Constipation
• Nausea
• Fatigue

Serious Side Effects:

• Slow or irregular heartbeat
• Shortness of breath
• Swelling of the ankles or feet
• Severe abdominal pain
• Signs of an allergic reaction (rash, itching, swelling, difficulty breathing)

Precautions

• Inform your doctor about any existing medical conditions or medications you are taking before using Calan SR.
• Be cautious when driving or operating machinery until you know how Calan SR affects you, as it may cause dizziness or drowsiness.
• Monitor for signs of heart failure, such as swelling of the ankles or feet and shortness of breath and report these symptoms to your doctor.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Calan SR with your healthcare provider.

Storage Instructions

• Store Calan SR capsules at room temperature (20°C to 25°C) in a dry place, away from moisture and heat.
• Keep the capsules in their original packaging until ready to use.
• Do not use Calan SR if the capsules appear discolored, damaged, or show signs of deterioration.
• Keep Calan SR out of reach of children and pets.
• Dispose of any unused or expired medication properly, following local regulations or guidelines.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019152s041lbl.pdf