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Azor (amlodipine and olmesartan)

Indications

• Azor is a combination medication used to treat high blood pressure (hypertension).
• It helps to lower blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.

Dosage and Administration

• Take Azor exactly as prescribed by your doctor, typically once daily.
• Swallow the tablet whole with a full glass of water, with or without food.
• Follow a consistent schedule for taking Azor to maintain steady blood pressure control.
• Inform your doctor of any other medications you are taking to avoid potential interactions.
• Do not exceed the prescribed dose of Azor unless directed by your doctor.
• Do not take Azor if you are pregnant, planning to become pregnant, or breastfeeding without consulting your doctor.
• Avoid consuming grapefruit or grapefruit juice while taking Azor, as it may increase the levels of amlodipine in your blood.

Mechanism of Action

Azor combines two medications: amlodipine, a calcium channel blocker, and olmesartan, an angiotensin II receptor blocker (ARB). Amlodipine relaxes blood vessels, allowing blood to flow more easily, while olmesartan blocks the action of angiotensin II, a substance that narrows blood vessels and raises blood pressure. Together, they help to lower blood pressure.

Contraindications

• Do not take Azor if you are allergic to amlodipine, olmesartan, or any other components of the medication.
• Avoid Azor if you have a history of angioedema (severe swelling) associated with previous ARB therapy.
• Consult your doctor before using Azor if you have severe liver disease or kidney disease.

Side Effects

Common Side Effects

• Dizziness
• Swelling of the ankles or feet
• Headache
• Flushing
• Fatigue

Serious Side Effects

• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
• Symptoms of high potassium levels (weakness, slow or irregular heartbeat, confusion)
• Signs of kidney problems (changes in urine volume, blood in the urine, swelling of the feet or ankles)
• Symptoms of low blood pressure (dizziness, lightheadedness, fainting)
• Chest pain

Precautions

• Inform your doctor about your medical history, especially if you have liver disease, kidney disease, heart disease, or diabetes.
• Be cautious when driving or operating machinery, as Azor may cause dizziness or lightheadedness.
• Monitor your blood pressure regularly and report any significant changes to your doctor.
• Avoid alcohol while taking Azor, as it may increase the risk of side effects.

Storage Instructions

• Store Azor tablets at room temperature (15°C to 30°C) in their original container, tightly closed.
• Keep out of reach of children and pets.
• Protect from moisture and light.
• Do not use after the expiration date.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/022100s033lbl.pdf