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Aldomet (methyldopa)

Indications

• Aldomet is used to treat high blood pressure (hypertension).
• It helps prevent complications such as strokes, heart attacks, and kidney problems caused by high blood pressure.
• Aldomet is often prescribed when other blood pressure medications are not suitable or effective.

Dosage and Administration

• Take Aldomet exactly as prescribed by your doctor, typically 2-3 times a day.
• Swallow the tablets with a full glass of water, with or without food.
• Take your doses at the same time each day to maintain an even level of medication in your body.
• Follow your doctor’s instructions regarding regular monitoring of your blood pressure.
• Inform your doctor about all other medications you are taking to avoid potential interactions.
• Do not take more than the prescribed dose.
• Avoid alcohol as it can increase certain side effects of Aldomet.
• Do not skip doses or stop taking Aldomet suddenly without consulting your doctor.
• Do not use Aldomet if you have liver disease without consulting your doctor.
• Avoid operating heavy machinery or driving until you know how Aldomet affects you, as it can cause drowsiness.

Mechanism of Action

Aldomet contains Methyldopa, which is an antihypertensive medication. Methyldopa works by stimulating alpha-2 adrenergic receptors in the brain, which leads to reduced sympathetic outflow from the central nervous system. This causes relaxation of blood vessels, leading to a decrease in blood pressure.

Contraindications

• Do not use Aldomet if you are allergic to Methyldopa or any of its ingredients.
• Avoid using the medication if you have active liver disease, or a history of liver disorders related to methyldopa.
• Do not take the medication if you have a known pheochromocytoma (a type of adrenal gland tumor).
• Avoid using Aldomet if you have a history of depression unless advised by your doctor.

Side Effects

Common Side Effects:

• Drowsiness
• Dizziness
• Headache
• Weakness
• Dry mouth

Serious Side Effects:

• Severe allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing
• Signs of liver problems, such as yellowing of the skin or eyes, dark urine, severe abdominal pain
• Unusual tiredness or weakness
• Persistent fever, sore throat, or signs of infection
• Heart problems, such as chest pain or irregular heartbeat

Precautions

• Inform your doctor about all other medications you are using, including over-the-counter products and supplements.
• Notify your doctor if you have a history of liver disease, heart disease, kidney disease, or blood disorders.
• Use effective contraception if you have childbearing potential and discuss the risks if you are pregnant or planning to become pregnant.
• Monitor your blood pressure regularly and keep a record of your readings.
• If you experience symptoms such as persistent fever, sore throat, or signs of infection, contact your doctor immediately.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose. Do not double the dose to catch up.

Storage Instructions

• Store Aldomet at room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep the tablets in their original container, tightly closed.
• Store Aldomet out of reach of children and pets.
• Protect the tablets from moisture and light.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/13400s086lbl.pdf