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Viracept (nelfinavir mesylate)

Indications

Viracept tablets are used in combination with other antiretroviral medications for the treatment of HIV-1 infection in adults and children. The medication helps to decrease the amount of HIV in the body, which improves immune system function and reduces the risk of developing AIDS-related illnesses.

Ingredients

• Active Ingredient: Nelfinavir mesylate.
• Inactive Ingredients: Lactose monohydrate, magnesium stearate, povidone, sodium starch glycolate, calcium silicate, and other tablet excipients.

Dosage and Administration

• Take Viracept tablets as prescribed by your healthcare provider, typically 750 mg (three 250 mg tablets) taken three times daily or 1,250 mg (five 250 mg tablets) taken twice daily.
• Swallow the tablets whole with water, preferably with food to enhance absorption.
• If taking with a liquid, dissolve tablets in a small amount of water and stir until dispersed; drink immediately and rinse the glass with more water to consume all the medication.
• Do not skip doses or discontinue treatment without consulting your healthcare provider, as this may lead to drug resistance and treatment failure.
• Avoid using Viracept with other drugs that may interact negatively, such as certain statins, ergot derivatives, or medications that affect liver enzymes.
• Do not use it if you have a known allergy to nelfinavir or any of its components.

Mechanism of Action

Viracept (nelfinavir) is a protease inhibitor that works by blocking the protease enzyme, which is necessary for the virus to multiply and spread in the body. By inhibiting this enzyme, Viracept prevents the maturation of HIV particles, thereby reducing the viral load in the body.

Contraindications

• Severe Liver Impairment: Viracept is contraindicated in patients with severe liver disease due to the risk of worsened liver function.
• Known Hypersensitivity: Avoid use if you have a known hypersensitivity to nelfinavir or any other ingredient in the formulation.
• Drug Interactions: Do not use Viracept with drugs that are highly dependent on CYP3A for clearance and for which elevated plasma levels are associated with serious and/or life-threatening events.

Side Effects

Common Side Effects:

• Diarrhea
• Nausea
• Abdominal pain
• Fatigue
• Rash

Serious Side Effects:

• Severe allergic reactions (e.g., rash, hives, difficulty breathing)
• Liver problems, including jaundice or severe liver inflammation
• Increased blood sugar levels, which may lead to new-onset diabetes or worsening of existing diabetes
• Changes in body fat distribution, such as increased fat in the upper back, neck, breasts, and around the abdomen

Precautions

• Monitor Blood Sugar: Regular monitoring of blood sugar levels is recommended, especially for diabetic patients, as Viracept can cause hyperglycemia.
• Liver Function Tests: Routine liver function tests should be conducted, particularly in patients with preexisting liver conditions.
• Sun Protection: Use sun protection measures, as some patients may experience increased sensitivity to sunlight.
• Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as there are risks associated with Viracept use during these periods.

Storage Instructions

• Store Viracept tablets at room temperature, between 15°C and 30°C (59°F and 86°F).
• Keep the medication in its original container, tightly closed, and away from excessive moisture and heat.
• Keep out of reach of children and pets to avoid accidental ingestion.

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How to Order Viracept Online in Canada?

Online

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Phone

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Fax

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References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021503s006lbl.pdf