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Formulation : Tablet
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What is Relpax?

Relpax is used for the acute treatment of migraine headaches with or without aura. It can only be used as a treatment after a clear diagnosis of migraine has been established. 

This brand-name medication can only be obtained with a doctor’s prescription.

How does Relpax work on migraines? 

Relpax contains the active ingredient Eletriptan, which belongs to a class of drugs called Serotonin 5-HT-Receptor Agonists (triptans); Antimigraine Agents. 

Relpax works by specifically acting at 5-HT1B/1D/1F receptors on intracranial blood vessels and sensory nerve endings. This leads to tightening of the blood vessels (vasoconstriction) and preventing the release of sensory chemicals to relieve pain associated with acute migraine.

Relpax Dosage

Relpax comes in tablet form and is available in two strengths: 20 mg and 40 mg.

The recommended initial dose is either Relpax 20 mg or 40 mg, taken once when you first notice having a migraine headache. If the first dose does not work to relieve your headache, you can take a second dose of Relpax after 2 hours. Do not take more than 40 mg at one time. The maximum dose of Relpax in a day is 80 mg.

Relpax is only taken when you experience migraine headaches. This is not for daily use.

Cautions when using Relpax

Do not take Relpax if you are allergic to it or to any of its active and inactive ingredients.

This medication should not be taken by people who have silent heart ischemia or a history of heart attack, chest pain (angina pectoris) and coronary artery vasospasm (Prinxmetal angina), stroke, or transient ischemic attacks (TIAs), peripheral vascular syndromes such as Raynaud’s syndrome, ischemic bowel disease, basilar, certain types of migraine headaches such as basilar, hemiplegic, or ophthalmologic, history or have heart disease such as heart valve disease or congenital heart disease, hypertension (elevated blood pressure), severe liver disease.

Do not take Relpax if you have taken any of these medications in the past 72 hours: ketoconazole, itraconazole, clarithromycin, troleandomycin, nefazodone, nelfinavir, or ritonavir.

You should not take this medication within 24 hours before or after using another medicine for migraine headaches such as ergot medicine (dihydroergotamine, ergotamine, ergonovine, methylergonovine) and medicines like eletriptan such as almotriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan.

If you are also taking stimulant medications, herbal products, opioids, or medication for depression, mental illness, Parkinson’s disease, serious infections, migraine headaches, or prevention of nausea and vomiting, be sure your doctor is aware. These medications may interact with Eletriptan and result in a serious condition known as serotonin syndrome.

Inform your doctor if you have ever had liver or kidney disease, heart problems, and risk factors for coronary artery disease (CAD) such as elevated blood pressure, high cholesterol, menopause, diabetes, being overweight, smoking, a family history of CAD, or a man older than 40.

If you are pregnant or planning to become one, let your doctor know. It is unknown if Relpax will harm an unborn baby.

Breastfeeding while taking Eletriptan may be unsafe because this medication passes into breast milk which may affect the baby. Discuss with your doctor the risk and the best thing to do.

Relpax side effects

Like most medications, Relpax may cause some unwanted side effects. Some may simply go away after the body has adjusted to the drug. Some may need immediate medical attention.

Here are the common side effects associated with Relpax use: 

-Feeling weak or tired 




-Stomach pain, pressure, or cramps 

-Tightness, pain, or pressure in the throat, neck, or jaw

Serious side effects associated with Relpax use: 

-Heart attack manifested by shortness of breath, chest pain, tightness, pressure, cold sweat, and feeling dizzy or lightheaded. 

-Changes in your heart rhythm are shown by feeling dizzy, fainting, palpitations, and chest pain. 

-Stroke or bleeding in the brain shown by sudden weakness or numbness on one side of the body, confusion, trouble speaking and walking, changes in vision, sudden severe headache, and facial drooping. 

-Blood circulation problems such as Raynaud’s syndrome manifested by numbness in your fingers or toes, numbness or weakness in the legs, blue-colored or pale fingers or toes, and pain or cramping in the legs. 

-Gastrointestinal problems are shown by diarrhea with blood, constipation, nausea or vomiting, sudden stomach pain, weight loss, and fever. 

-Serotonin syndrome is manifested by rapid heart rate, sweating, restlessness or agitation, blood pressure changes, lack of coordination, and hallucination. 

-High blood pressure (hypertension) is shown by severe headache, dizziness, chest pain, shortness of breath, changes in vision, confusion, and a pounding sound in your ears or pounding feeling in your chest. 

-Allergic reaction is shown by rash, itching, swelling of the face, lips, tongue, or throat swelling, severe dizziness, and trouble breathing. 

If you have any of these conditions and symptoms, seek medical help right away.

How much does Relpax cost in Canada? 

Relax price varies depending on your dose which is determined by your physician. Check the list of prices at the top to see how much you can save when you order your medication from us.

Frequently asked questions about Relpax 

Is Relpax an NSAID? 

Relpax (eletriptan) belongs to a class of drugs called Serotonin 5-HT-Receptor Agonists or triptans.

How many Relpax can you take in a week? 

Using triptan drugs too often, such as Eletriptan can lead to medication overuse headaches (MOH). To avoid getting MOH, try not to use triptan medication more than 2 or 3 times per week or 10 days each month.   

Once you and your healthcare provider find that Relpax is safe and effective for you, you may take it up to three times a month. If you take Relpax 10 or more days a month, the frequency and severity of headaches could increase.

How long does Relpax stay in your system? 

Relpax (eletriptan) has a terminal elimination half-life of approximately 4 hours. Half-life is the time it takes for the amount of the drug’s active substance in the body to reduce by half.   

The mean renal clearance (CLR) after oral administration is approximately 3.9 L/h.

How fast does Relpax work? 

Many people experience migraine relief with Relpax in 2 hours. For some people, this medication begins to work in 30 minutes. 

Additional information

Brand Name:


Scientific Name:


Other Names:

Eletriptan, Relpax


20mg, 40mg

Quantities Available:

6, 12, 18, 24, 36



The information above is provided by third parties to for Relpax (Eletriptan). This information is for general purposes only and is not intended to replace a physician's advice. Always consult with your doctor or a qualified health care professional if you need advice on any medical concerns.