Are you Looking to Buy Rapamune (Sirolimus) from PrescriptionPoint.

Rapamune (sirolimus) 

Indications 

• Rapamune is used to prevent rejection of a kidney transplant. It is typically used in combination with other medications to suppress the immune system and help the body accept the new organ. 
• It is also indicated for the treatment of LAM, a rare, progressive lung disease that affects women of childbearing age. 

Dosage and Administration 

• Take Rapamune exactly as prescribed by your doctor. 
• Swallow the tablets whole with or without food. 
• Take the medication at the same time each day for the best results. 
• Inform your doctor of all medications, supplements, and herbal products you are currently taking. : 
• Do not crush, chew, or break the tablets, as this can affect the drug’s effectiveness. 
• Avoid taking more than the prescribed dose to prevent potential side effects. 
• Do not stop taking Rapamune without consulting your doctor, even if you feel well. 
• Avoid consuming grapefruit or grapefruit juice while taking Rapamune, as it can interfere with the drug’s metabolism. 
• Do not skip doses; take the tablet consistently as prescribed. 

Mechanism of Action 

Rapamune (Sirolimus) is an immunosuppressant that works by inhibiting the activation and proliferation of T lymphocytes, which play a key role in the body’s immune response. By blocking the mammalian target of rapamycin (mTOR) pathway, Rapamune reduces the body’s ability to reject transplanted organs and helps to manage LAM. 

Contraindications 

• Do not use the medication if you are allergic to Sirolimus or any ingredients in Rapamune. 
• Avoid use if you have severe liver problems without consulting your doctor. 
• Consult your doctor if you have a history of lung disease or infections before taking this medication. 
• Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. 

Side Effects 

Common Side Effects: 

• High blood pressure 
• Elevated cholesterol and triglyceride levels 
• Abdominal pain 
• Diarrhea 
• Joint pain 
• Anemia 
• Headache 
• Nausea 

Serious Side Effects: 

• Signs of infection (fever, chills, sore throat) 
• Unusual bleeding or bruising 
• Severe abdominal pain 
• Shortness of breath or chest pain 
• Allergic reactions (rash, itching, swelling of the face/tongue/throat) 
• Liver or kidney dysfunction 

Precautions 

• Inform your doctor of any existing health conditions, especially liver disease, lung disease, or infections. 
• Regularly monitor blood levels, blood pressure, and kidney function while taking Rapamune. 
• Use effective birth control during treatment and for 12 weeks after the last dose to avoid pregnancy. 
• Avoid exposure to sunlight and UV light, as Rapamune can increase the risk of skin cancer. Use sunscreen and wear protective clothing. 

Storage Instructions 

• Store Rapamune tablets at room temperature between 68°F and 77°F (20°C and 25°C). 
• Keep the medication in its original container, tightly closed, and away from moisture and light. 
• Do not store the tablets in the bathroom to avoid exposure to humidity. 
• Keep out of reach of children and pets. 

References 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021083s059,021110s076lbl.pdf