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Precose (acarbose)

Indications

Precose is used to control blood sugar levels in adults with type 2 diabetes. It is taken in conjunction with diet and exercise to improve blood glucose control.

Dosage and Administration

• Take Precose exactly as prescribed by your doctor.
• Swallow the tablet with the first bite of each main meal.
• Follow your doctor’s instructions regarding the timing of doses, typically three times daily.
• Monitor your blood sugar levels regularly as advised by your healthcare provider.
• Inform your doctor of all medications, supplements, and herbal products you are currently taking.
• Do not take Precose if you skip a meal, as it is intended to work with food intake.
• Avoid taking more than the prescribed dose to prevent potential side effects.
• Do not crush or chew the tablets, as it may affect the drug’s effectiveness.
• Do not stop taking Precose without consulting your doctor, even if you feel well.

Mechanism of Action

Precose (Acarbose) is an alpha-glucosidase inhibitor that works by slowing down the breakdown of complex carbohydrates into simple sugars in the intestines. This results in a slower and lower rise in blood glucose levels after meals, helping to improve overall blood sugar control in people with type 2 diabetes.

Contraindications

• Do not use it if you are allergic to Acarbose or any ingredients in Precose.
• Avoid if you have inflammatory bowel disease, colonic ulceration, or partial intestinal obstruction.
• Not recommended for patients with chronic intestinal diseases associated with marked disorders of digestion or absorption.
• Consult your doctor if you have liver problems before taking this medication.

Side Effects

Common Side Effects:

• Flatulence (gas)
• Diarrhea
• Abdominal pain
• Bloating

Serious Side Effects:

• Severe abdominal pain
• Yellowing of the skin or eyes (jaundice)
• Unusual bleeding or bruising
• Severe constipation
• Allergic reactions (rash, itching, swelling of the face/tongue/throat)

Precautions

• Regularly monitor blood sugar levels and be aware of the symptoms of low blood sugar, especially when used with other diabetes medications.
• Use glucose (dextrose) rather than sucrose (table sugar) to treat low blood sugar episodes, as Precose can delay the digestion of sucrose.
• Follow your doctor’s dietary recommendations closely to minimize gastrointestinal side effects.

Storage Instructions

• Store Precose tablets at room temperature between 68°F and 77°F (20°C and 25°C).
• Keep the medication in its original container, tightly closed, and away from moisture and light.
• Do not store it in the bathroom to avoid exposure to humidity.
• Keep out of reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020482s025lbl.pdf