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Penlac Nail Lacquer (ciclopirox)

Indications

• Penlac Nail Lacquer is prescribed for the treatment of fungal infections of the toenails and fingernails (onychomycosis).
• It helps inhibit the growth of fungi responsible for the infection, restoring the health and appearance of the affected nails.

Dosage and Administration

• Apply Penlac Nail Lacquer solution once daily, preferably at bedtime.
• Ensure the affected nail(s) are clean and dry before application.
• Use the applicator brush provided to cover the entire nail surface and the surrounding skin with a thin layer of lacquer.
• Allow the lacquer to dry completely before covering with socks or shoes.
• Do not apply Penlac Nail Lacquer to broken or irritated skin around the nail.
• Avoid getting Penlac Nail Lacquer in your eyes, mouth, or nose. If accidental exposure occurs, rinse thoroughly with water.
• Do not use nail polish or other nail products while using the solution, as they may interfere with treatment.

Mechanism of Action

Penlac Nail Lacquer contains Ciclopirox, which works by disrupting the fungal cell membrane, leading to the death of the fungal cells. This helps eliminate the fungal infection in the nails.

Contraindications

• Do not use Penlac Nail Lacquer if you are allergic to Ciclopirox or any other ingredients in the lacquer.
• Avoid Penlac if you have a history of hypersensitivity reactions to antifungal medications.
• Penlac Nail Lacquer is not recommended for use in children under 10 years old without medical advice.

Side Effects

Common Side Effects:

• Mild itching or burning sensation at the application site
• Redness or irritation around the treated nail
• Changes in the appearance of the nail (discoloration)

Serious Side Effects:

• Severe allergic reactions (swelling of the face, lips, tongue, difficulty breathing)
• Severe skin reactions (blistering, peeling)
• Worsening of the fungal infection

Precautions

• Inform your doctor about any existing skin conditions or allergies before starting treatment with Penlac Nail Lacquer.
• Do not share Penlac Nail Lacquer with others, as it is prescribed based on the specific fungal infection.
• Keep nails trimmed and clean to improve the effectiveness of Penlac treatment.

Storage Instructions

• Store Penlac Nail Lacquer solution at room temperature between 68°F to 77°F (20°C to 25°C).
• Keep the bottle tightly closed when not in use and store away from heat and direct sunlight.
• Keep out of reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/21022s004lbl.pdf