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Famvir (famciclovir)

Indications

Famvir tablets are prescribed for the following conditions:

• Herpes Simplex Virus (HSV) Infections:
  •  Treatment of recurrent genital herpes in immunocompetent adults.
  • Suppression of recurrent genital herpes in immunocompetent adults.
  • Treatment of herpes labialis (cold sores) in immunocompetent adults.

• Herpes Zoster (Shingles):
  • Treatment of acute herpes zoster (shingles) in immunocompetent adults.

• Varicella-Zoster Virus (VZV) Infections:
  •   Treatment of chickenpox (varicella) in immunocompetent adults.

Dosage and Administration

• Follow your doctor’s prescription exactly. Famvir dosage and duration of treatment depend on the specific condition being treated.
• Begin treatment as soon as possible after the onset of symptoms for maximum effectiveness.
• Complete the full course of treatment, even if symptoms improve before the medication is finished.
• Take with or without Food. Famvir can be taken with or without food.
• Do not skip doses. Missing doses can reduce the effectiveness of the treatment. If you miss a dose, take it as soon as you remember.
• Avoid Overdose. Do not take more than the prescribed amount of Famvir.
• Do not share medication. Do not share Famvir with others, even if they have similar symptoms.
• Avoid alcohol. Limit alcohol consumption while taking Famvir, as it may increase the risk of side effects.

Mechanism of Action

Famvir is an antiviral medication. It works by inhibiting the replication of herpes viruses, including herpes simplex viruses (HSV-1 and HSV-2) and varicella-zoster virus (VZV). Famvir is converted into its active form, penciclovir, which interferes with viral DNA synthesis, thereby stopping the virus from multiplying.

Contraindications

Famvir should not be used if:

• You are allergic to Famciclovir: Any known hypersensitivity to Famciclovir or any component of Famvir tablets.
• You have severe kidney disease: Consult your doctor before taking Famvir if you have severe kidney impairment.
• You are pregnant or breastfeeding: Famvir should be used during pregnancy or breastfeeding only if the potential benefits justify the potential risks to the fetus or infant.

Side Effects

Common Side Effects:

• Headache
• Nausea
• Diarrhea
• Fatigue
• Dizziness

Serious Side Effects:

• Allergic Reactions: Rash, itching, swelling, severe dizziness, or trouble breathing.
• Changes in Blood Cell Counts: Symptoms may include unusual bruising or bleeding, pale skin, weakness, or signs of infection.
• Liver Problems: Yellowing of the skin or eyes (jaundice), dark urine, severe stomach pain.

Precautions

• Inform Your Doctor: Inform your doctor about any medical conditions you have, especially kidney problems or a weakened immune system.
• Monitor for Symptoms: Be vigilant for any signs of allergic reactions, changes in blood cell counts, or liver problems while taking Famvir.
• Avoid Transmission: To prevent spreading the infection, avoid close physical contact with others, especially those who are immunocompromised or pregnant, during active herpes outbreaks.
• Avoid Sexual Contact: Refrain from sexual activity during herpes outbreaks to reduce the risk of transmitting the virus to others.
• Practice Good Hygiene: Wash your hands frequently, especially after touching affected areas, to prevent spreading the virus to other parts of the body or to others.

Storage Instructions

• Keep Famvir tablets at a temperature between 68°F to 77°F (20°C to 25°C).
• Store in a dry place; avoid bathrooms and kitchens where humidity is high.
• Store the tablets in their original container, tightly closed, to protect from moisture and light.
• Ensure that the medication is stored safely out of the reach of children and pets.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020363s037lbl.pdf