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Albenza (albendazole)

Indications

• Albenza is used to treat a variety of parasitic worm infections, including neurocysticercosis (caused by pork tapeworm) and hydatid disease (caused by dog tapeworm).
• It helps eliminate tapeworms, roundworms, and hookworms from the body.
• Albenza is prescribed to treat certain infections that can affect the liver, lungs, and other organs.

Dosage and Administration

• Take Albenza exactly as prescribed by your doctor, typically with food to increase absorption.
• Take twice daily for 8-30 days, as directed by your healthcare provider, for neurocysticercosis.
• Taken twice daily in 28-day cycles, with a 14-day break between cycles for hydatid disease.
• Follow your doctor’s instructions on the duration and schedule of treatment.
• Have regular blood tests as instructed by your doctor to monitor your response and check for side effects.
• Do not take more than the prescribed dose.
• Avoid consuming grapefruit juice while taking Albenza, as it can increase the risk of side effects.
• Do not skip doses or stop taking Albenza without consulting your doctor, even if you feel better.

Mechanism of Action

Albenza contains Albendazole, which is an anthelmintic (anti-worm) medication. It works by inhibiting the microtubule formation in the intestinal cells of parasites, thereby preventing them from absorbing glucose and other nutrients. This leads to the depletion of the parasite’s energy stores, resulting in their eventual death and elimination from the body.

Contraindications

• Do not use Albenza if you are allergic to Albendazole, Benzimidazoles, or any of its ingredients.
• Avoid using the medication if you have liver disease without consulting your doctor.
• Do not take Albenza if you are pregnant, as it can harm the unborn baby.

Side Effects

Common Side Effects:

• Headache
• Dizziness
• Nausea
• Vomiting
• Abdominal pain

Serious Side Effects:

• Severe allergic reactions, including rash, itching, swelling, severe dizziness, and trouble breathing
• Signs of liver problems, such as yellowing of the skin or eyes, dark urine
• Unusual tiredness or weakness
• Severe abdominal pain
• Seizures

Precautions

• Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements.
• Notify your doctor if you have a history of liver disease, bone marrow suppression, or blood disorders.
• Use effective contraception during treatment and for at least 1 month after the last dose if you are of childbearing potential.
• If you experience signs of infection, such as fever or sore throat, contact your doctor immediately.
• Discuss the risks and benefits of using Albenza if you are breastfeeding.

Storage Instructions

• Store Albenza at room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep the tablets in their original container, tightly closed.
• Store Albenza out of reach of children and pets.
• Protect the tablets from moisture and light.

References

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020666s012lbl.pdf